wizyta

od 2020-09-20

Title: SAXS study of selected cationic surfactant influence on the DSPC-based model phospholipid system

Source: Solid State Phenomena

Year : 2007

Abstract:

The phase behaviour of lipid bilayer systems prepared with 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) with dodecyldimethyl(benzyloxymethyl)ammonium chloride (BzMDDAC) (at concentrations 0.1, 1 and 5%) has been studied by small angle X-ray scattering and differential scanning calorimetry. The SAXS and DSC results of the hydrated 10% DSPC revealed one typical phase transition corresponding to melting of the hydrocarbon chains at 5 5 degrees C. In the system of 10% DSPC - 0.1% BzMDDAC the main transition was somewhat shifted towards lower temperatures, while at 1% concentration of BzMDDAC in the mixture, the lamellar phase disappeared, as evidenced by SAXS and DSC. The increase in BzMDDAC concentration to 5% in the mixture with 10% DSPC resulted in formation of a new lamellar phase.

DOI: 10.4028/3-908451-40-x.257   (Pobrane:  2021-01-10)